Gliclazide
Molecular formula:C15H21N3O3S
Molecular weight:323.412 g/mol
CAS NO:21187-98-4
Gliclazide is a hypoglycemic agent of the sulfonylurea group.Gliclazide is a sulphonylurea hypoglycaemic given orally for non-insulin dependent diabetes mellitus (type 2). Gliclazide stimulates the secretion of insulin from functional pancreatic β-cells, increasing the sensitivity of β-cells to glucose stimulation.Gliclazide may be able to maintain its effect on insulin secretion resulting in long-term hypoglycaemic activity and some extrapancreatic effects.Gliclazide also reduces platelet adhesiveness and aggregation at normal therapeutic doses in man.
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