10-Hydroxycamptothecin
Botanical source: Camptotheca acuminata Decne
CAS NO: 7689-03-4
Molecular formula: C20H16N2O5
Appearance: Light Yellow Crystal Powder
Solubility: Insoluble in water, its sodium salt is the water-soluble, its organic solution has blue fluorescence.
Functions:
10-hydroxycamptothecin is the derivative of camptothecine that is a micro-alkaloid from camptotheca Acuminate (a tree native to mainland China). Is a kind of pharmaceutical intermediate, an alkaloid originally isolated from the Camptotheca acuminata, exerted inhibitory effects on DNA topoisomerase (Topo )and has anticancer activity in vitro and in vivo.
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